- Abstract:
-
Invariant natural killer T (iNKT) cells are powerful immunomodulatory cells that in mice regulate a variety of immune responses, including acute GVHD (aGVHD). However, their clinical relevance and in particular their role in clinical aGVHD are not known. We studied whether peripheral blood stem cell (PBSC) graft iNKT-cell dose affects on the occurrence of clinically significant grade II-IV aGVHD in patients (n = 57) undergoing sibling, HLA-identical allogeneic HSCT. In multivariate analysis, ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 305.9KB)
-
- Publisher copy:
- 10.1182/blood-2011-11-389304
-
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- Publisher:
- American Society for Hematology Publisher's website
- Journal:
- Blood Journal website
- Volume:
- 119
- Issue:
- 21
- Pages:
- 5030-5036
- Publication date:
- 2012-05-05
- DOI:
- EISSN:
-
1528-0020
- ISSN:
-
0006-4971
- URN:
-
uuid:8b0e859c-191c-4bb1-b746-9ced564d8796
- Source identifiers:
-
508070
- Local pid:
- pubs:508070
- Language:
- English
- Keywords:
- Copyright holder:
- American Society of Hematology
- Copyright date:
- 2012
- Notes:
- © 2012 by The American Society of Hematology
Journal article
Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
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Leukaemia and Lymphoma Research
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National Institute of Health Research
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Leuka
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