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Journal article

Whole-brain magnetic resonance spectroscopic imaging measures are related to disability in ALS.

Abstract:

OBJECTIVE: To demonstrate the sensitivity of a recently developed whole-brain magnetic resonance spectroscopic imaging (MRSI) sequence to cerebral pathology and disability in amyotrophic lateral sclerosis (ALS), and compare with measures derived from diffusion tensor imaging. METHODS: Whole-brain MRSI and diffusion tensor imaging were undertaken in 13 patients and 14 age-similar healthy controls. Mean N-acetylaspartate (NAA), fractional anisotropy, and mean diffusivity were extracted from the...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Neurology
Volume:
80
Issue:
7
Pages:
610-615
Publication date:
2013-02-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:8b061a99-0238-4eb7-914f-58542dd2cf09
Source identifiers:
374228
Local pid:
pubs:374228

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