Journal article
Accuracy of haplotype reconstruction from haplotype-tagging single-nucleotide polymorphisms
- Abstract:
-
Many investigators are now using haplotype-tagging single-nucleotide polymorphism (htSNPs) as a way of screening regions of the genome for association with disease. A common approach is to genotype htSNPs in a study population and to use this information to draw inferences about each individual's haplotypic makeup, including SNPs that were not directly genotyped. To test the validity of this approach, we simulated the exercise of typing htSNPs in a large sample of individuals and compared the...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Version of record, pdf, 431.2KB)
-
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Funding
Medical Research Council
More from this funder
Bibliographic Details
- Publisher:
- University of Chicago Press Publisher's website
- Journal:
- American Journal of Human Genetics Journal website
- Volume:
- 76
- Issue:
- 3
- Pages:
- 438-448
- Publication date:
- 2005-03-01
- ISSN:
-
0002-9297
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:8afb07bb-89b1-4d04-b40d-35d568607cbb
- Local pid:
- ora:1391
- Deposit date:
- 2008-03-14
Related Items
Terms of use
- Copyright holder:
- The American Society of Human Genetics
- Copyright date:
- 2005
- Notes:
- Citation: Forton, J. et al. (2005) 'Accuracy of haplotype reconstruction from haplotype-tagging single-nucleotide polymorphisms', American Journal of Human Genetics, 76 (3), 438-448. [Available at http://www.journals.uchicago.edu/AJHG/].
If you are the owner of this record, you can report an update to it here: Report update to this record