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Is T-cell memory maintained by crossreactive stimulation?

Abstract:

Whether or not T- and B-cell memory is antigen driven remains unresolved. Recent studies indicate that, in humans, naive and memory T cells can be distinguished by their expression of different CD45 isoforms. Extensive phenotypic analysis of naive and memory T cells shows that the latter express greater amounts of several adhesion molecules as well as low levels of several antigens indicative of activation. These features suggest to Peter Beverley that memory T cells may be more readily activ...

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Journal:
Trends in Immunology
Volume:
11
Issue:
C
Pages:
203-205
Publication date:
1990-01-01
ISSN:
1471-4906
Language:
English
Pubs id:
pubs:94522
UUID:
uuid:8afa2786-2ffd-4468-a70a-98436cca5a90
Local pid:
pubs:94522
Source identifiers:
94522
Deposit date:
2012-12-20

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