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Dynamical modeling of syncytial mitotic cycles in Drosophila embryos.

Abstract:

Immediately following fertilization, the fruit fly embryo undergoes 13 rapid, synchronous, syncytial nuclear division cycles driven by maternal genes and proteins. During these mitotic cycles, there are barely detectable oscillations in the total level of B-type cyclins. In this paper, we propose a dynamical model for the molecular events underlying these early nuclear division cycles in Drosophila. The model distinguishes nuclear and cytoplasmic compartments of the embryo and permits explora...

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Publication status:
Published

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Publisher copy:
10.1038/msb4100171

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Molecular systems biology
Volume:
3
Pages:
131
Publication date:
2007-01-01
DOI:
EISSN:
1744-4292
ISSN:
1744-4292
Source identifiers:
100409
Language:
English
Keywords:
Pubs id:
pubs:100409
UUID:
uuid:8ad4a816-3c8f-42ee-8dd6-96f1d5037bdb
Local pid:
pubs:100409
Deposit date:
2012-12-19

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