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Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

Abstract:

Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a custom Illumina array (iCOGS) in blood DNA from 25,074 prostate cancer cases and 24,272 controls from the international PRACTICAL Consortium. Twenty-three new prostate cancer susceptibility loci were identified at genome-wide significance (P < 5 × 10(-8)). More than 70 prostate cancer susceptibility loci, explaini...

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Publication status:
Published

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Publisher copy:
10.1038/ng.2560

Authors


Benlloch, S More by this author
Saunders, EJ More by this author
Leongamornlert, DA More by this author
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Journal:
Nature genetics
Volume:
45
Issue:
4
Pages:
385-391e2
Publication date:
2013-04-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:8acca901-0083-4749-95c5-c314d4304b9a
Source identifiers:
390879
Local pid:
pubs:390879

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