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Journal article

A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes.

Abstract:

Cell surface molecules of eukaryotic cells have been considered to be integrated into the membrane bilayer by a transmembrane protein sequence. The Thy-1 antigen of rodent thymocytes and brain was the first eukaryotic membrane molecule for which biochemical data clearly suggested membrane integration via a nonprotein tail. Direct evidence is now presented showing that a glycophospholipid structure is attached to the carboxyl-terminal cysteine residue and that 31 carboxyl-terminal amino acids ...

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Publication status:
Published

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Publisher copy:
10.1126/science.2865810

Authors


Barclay, AN More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Williams, AF More by this author
Journal:
Science (New York, N.Y.)
Volume:
230
Issue:
4729
Pages:
1003-1008
Publication date:
1985-11-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:8abcabdb-ba3d-4361-8a25-bc1aed3be06a
Source identifiers:
422149
Local pid:
pubs:422149

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