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Immune-endocrine biomarkers as predictors of frailty and mortality: a 10-year longitudinal study in community-dwelling older people.

Abstract:

Frailty is a multidimensional geriatric syndrome characterised by a state of increased vulnerability to disease. Its causes are unclear, limiting opportunities for intervention. Age-related changes to the immune-endocrine axis are implicated. This study investigated the associations between the immune-endocrine axis and frailty as well as mortality 10 years later among men and women aged 65 to 70 years. We studied 254 participants of the Hertfordshire Ageing Study at baseline and 10-year foll...

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Publication status:
Published

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Publisher copy:
10.1007/s11357-012-9396-8

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Journal:
Age (Dordrecht, Netherlands)
Volume:
35
Issue:
3
Pages:
963-971
Publication date:
2013-06-05
DOI:
EISSN:
1574-4647
ISSN:
0161-9152
URN:
uuid:8a9d2205-4bf2-4618-834f-72e81d3504bc
Source identifiers:
316444
Local pid:
pubs:316444

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