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Journal article

Behavioral effects of aminochrome and dopachrome injected in the rat substantia nigra.

Abstract:

The exact mechanism of cell death in neurodegenerative diseases remains obscure, although there is evidence that their pathogenesis may involve the formation of free radicals originating from the oxidative metabolism of catecholamines. The purpose of this study was to evaluate the degree of neurodegenerative changes and behavioral impairments induced by unilateral injection into the rat substantia nigra of cyclized o-quinones, aminochrome and dopachrome, derived from oxidizing dopamine and L-...

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Journal:
Pharmacology, biochemistry, and behavior
Volume:
73
Issue:
4
Pages:
843-850
Publication date:
2002-11-01
DOI:
EISSN:
1873-5177
ISSN:
0091-3057
Source identifiers:
425174
Language:
English
Keywords:
Pubs id:
pubs:425174
UUID:
uuid:8a8cb77a-cce8-4ea4-84fc-465bfe3b980a
Local pid:
pubs:425174
Deposit date:
2013-11-16

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