Journal article
Predictive value of telomere length on outcome following acute myocardial infarction: Evidence for contrasting effects of vascular vs. blood oxidative stress
- Abstract:
-
Aims: Experimental evidence suggests that telomere length (TL) is shortened by oxidative DNA damage, reflecting biological aging. We explore the value of blood (BTL) and vascular (VTL) TL as biomarkers of systemic/vascular oxidative stress in humans and test the clinical predictive value of BTL in acute myocardial infarction (AMI). Methods and Results: In a prospective cohort of 290 patients surviving recent AMI, BTL measured on admission was a strong predict... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ British Heart Foundation
More from this funder
Funding agency for:
Antoniades, C
Grant:
ITN network RADOX
PG/13/56/30383toCA
FS/16/15/32047
+ National Institute for Health Research Oxford Biomedical Research Centre
More from this funder
Funding agency for:
Channon, K
Antoniades, C
Grant:
ITN network RADOX
ITN network RADOX
+ European Commission
More from this funder
Funding agency for:
Sanna, F
Channon, K
Antoniades, C
Grant:
ITN network RADOX
ITN network RADOX
ITN network RADOX
+ BHF Centre of Research Excellence Oxford
More from this funder
Funding agency for:
Margaritis, M
Antoniades, C
Grant:
RE/08/004
ITN network RADOX
RE/08/004 to
MM/CA
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- European Heart Journal Journal website
- Volume:
- 38
- Issue:
- 41
- Pages:
- 3094–3104
- Publication date:
- 2017-04-24
- Acceptance date:
- 2017-03-14
- DOI:
- EISSN:
-
1522-9645
- ISSN:
-
0195-668X
Item Description
- Keywords:
- Pubs id:
-
pubs:685955
- UUID:
-
uuid:8a72f885-6518-4787-9a9f-b1b37696e9e3
- Local pid:
- pubs:685955
- Source identifiers:
-
685955
- Deposit date:
- 2017-03-15
Terms of use
- Copyright holder:
- Margaritis et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 The Authors. Published by Oxford University Press on behalf of the European Society of Cardiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record