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Lovastatin-Mediated Changes in Human Tendon Cells

Abstract:

Statins are among the most widely prescribed drugs worldwide. Numerous studies have shown their beneficial effects in prevention of cardiovascular disease through cholesterol-lowering and anti-atherosclerotic properties. Although some statin patients may experience muscle-related symptoms, severe side effects of statin therapy are rare, primarily due to extensive first-pass metabolism in the liver. Skeletal muscles appear to be the main site of side effects; however, recently some statin-rela...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/jcp.25010

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Orthopaedic Research UK More from this funder
National Institute for Health and Research More from this funder
Publisher:
Wiley Publisher's website
Journal:
JOURNAL OF CELLULAR PHYSIOLOGY Journal website
Volume:
230
Issue:
10
Pages:
2543-2551
Publication date:
2015-06-23
DOI:
ISSN:
0021-9541
URN:
uuid:8a6df6be-112f-46d0-a41d-01d01aed248c
Source identifiers:
539319
Local pid:
pubs:539319

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