Low circulating IGF-I levels in hyperthyroidism are associated with decreased GH response to GH-releasing hormone.

Journal article

OBJECTIVE: Several abnormalities in the GH response to pharmacological stimuli have been described in hyperthyroidism. Both normal and high serum IGF-I levels have been reported, as well as a decrease in IGF-I bioactivity. We have evaluated the GH response to GH-releasing hormone (GHRH) in hyperthyroid patients and the effects of hyperthyroidism on serum IGF-I levels. The possible relations between nutritional status, thyroid hormones and IGF-I levels were also investigated. We also studied t...

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Authors: Ramos-Dias, J; Yateman, M; Camacho-Hübner, C; Grossman, A; Lengyel, A

• Publication status: Published
• Journal: Clinical endocrinology
• Volume: 43
• Issue: 5
• Pages: 583-589
• Publication date: 1995-11-01
• DOI: 10.1111/j.1365-2265.1995.tb02923.x
• EISSN: 1365-2265
• ISSN: 0300-0664
• Language: English
• Keywords: Adolescent; Growth Hormone; Adrenergic beta-Antagonists; Case-Control Studies; Hyperthyroidism; Adult; Middle Aged; Female; Male; Growth Hormone-Releasing Hormone; Body Weight; Propranolol; Insulin-Like Growth Factor I; Nutritional Status; Humans; Body Composition