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Journal article

The correlation between baseline score and post-intervention score, and its implications for statistical analysis

Abstract:
Background When using a continuous outcome measure in a randomised controlled trial (RCT), the baseline score should be measured in addition to the post-intervention score, and it should be analysed using the appropriate statistical analysis.

Methods We derive the correlation between the change score and baseline score and show that there is always a correlation (usually negative) between the change score and baseline score. We discuss the followin... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-018-3108-3

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Oxford college:
Kellogg College
Role:
Author
ORCID:
0000-0001-5595-8468
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering
Role:
Author
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
43
Issue:
20
Publication date:
2019-01-11
Acceptance date:
2018-12-06
DOI:
EISSN:
1745-6215
Source identifiers:
959298

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