Journal article
Toll-like receptor activation by generalized modules for membrane antigens from lipid a mutants of salmonella enterica serovars typhimurium and enteritidis
- Abstract:
-
Invasive nontyphoidalSalmonella(iNTS) disease is a neglected disease with high mortality in children and HIV-positive individuals in sub-Saharan Africa, caused primarily by Africa-specific strains ofSalmonella entericaserovars Typhimurium and Enteritidis. A vaccine using GMMA (generalized modules for membrane antigens) fromS.Typhimurium andS.Enteritidis containing lipid A modifications to reduce potentialin vivoreactogenicity is under development. GMMA with penta-acylated lipid A showed the g...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.4MB)
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- Publisher copy:
- 10.1128/CVI.00023-16
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Authors
Funding
Novartis
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Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Clinical and vaccine immunology Journal website
- Volume:
- 23
- Issue:
- 4
- Pages:
- 304-314
- Publication date:
- 2016-04-01
- Acceptance date:
- 2016-01-30
- DOI:
- EISSN:
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1556-679X
- ISSN:
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1556-6811
- Source identifiers:
-
605841
Item Description
- Language:
- English
- Pubs id:
-
pubs:605841
- UUID:
-
uuid:8a3b7bd2-7c6e-4049-84a7-8e32e90c9c25
- Local pid:
- pubs:605841
- Deposit date:
- 2016-05-03
Terms of use
- Copyright holder:
- Rossi et al
- Copyright date:
- 2016
- Notes:
-
© 2016 Rossi et al. This is an open-access article distributed under the
terms of the
Creative Commons Attribution 4.0 International license
- Licence:
- CC Attribution (CC BY)
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