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Clinical features, diagnosis, treatment and molecular studies in paediatric Cushing's syndrome due to primary nodular adrenocortical hyperplasia.

Abstract:

BACKGROUND: Primary nodular adrenocortical hyperplasia (PNAH) is a well recognized, but infrequently studied cause of paediatric Cushing's syndrome (CS). OBJECTIVE: To assess presentation, diagnosis, radiological imaging, treatment and molecular analysis of patients with childhood-onset CS due to PNAH. PATIENTS: Four males and two females (median age 12.9 years, range 10.9-16.9 years) were studied. RESULTS: All had growth failure (mean height SDS -1.2; range -2.5-0.0), weight gain [mean body ...

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Publication status:
Published

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Journal:
Clinical endocrinology More from this journal
Volume:
61
Issue:
5
Pages:
553-559
Publication date:
2004-11-01
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
Language:
English
Keywords:
Pubs id:
pubs:138236
UUID:
uuid:8a31c41f-c5d6-4df2-8869-5729178e6697
Local pid:
pubs:138236
Source identifiers:
138236
Deposit date:
2012-12-19

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