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Journal article

Animal models of the neuromuscular junction, vitally informative for understanding function and the molecular mechanisms of congenital myasthenic syndromes

Abstract:

The neuromuscular junction is the point of contact between motor nerve and skeletal muscle, its vital role in muscle function is reliant on the precise location and function of many proteins. Congenital myasthenic syndromes (CMS) are a heterogeneous group of disorders of neuromuscular transmission with 30 or more implicated proteins. The use of animal models has been instrumental in determining the specific role of many CMS-related proteins. The mouse neuromuscular junction (NMJ) has been ext...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/ijms19051326

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Name:
Medical Research Council
Funding agency for:
Webster, R
Grant:
MR/M006824/1
Publisher:
MDPI
Journal:
International Journal of Molecular Sciences More from this journal
Volume:
19
Issue:
5
Article number:
1326
Publication date:
2018-04-29
Acceptance date:
2018-04-25
DOI:
EISSN:
1422-0067
ISSN:
1661-6596
Keywords:
Pubs id:
pubs:845720
UUID:
uuid:8a23eeb8-b470-43c0-957c-eee7b7d69fdf
Local pid:
pubs:845720
Source identifiers:
845720
Deposit date:
2018-05-03

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