Journal article
P667Impaired chronic hypoxic response in type 2 diabetic hearts is associated with inability to downregulate PPARa.
- Abstract:
-
Cardiovascular disease is the leading cause of mortality in type 2 diabetic patients. Metabolic changes and abnormal hypoxia signalling in the diabetic heart are hypothesised to decrease recovery following a myocardial infarction. Therefore the aim of this study was to investigate the cardiac metabolic adaptation to physiological hypoxia in diabetic rats. Type 2 diabetes was generated in rats using a high fat diet and low dose streptozotocin. Both control and diabetic rats were housed in hypo...
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- Publication status:
- Published
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- Publisher copy:
- 10.1093/cvr/cvu098.92
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Bibliographic Details
- Journal:
- Cardiovascular research
- Volume:
- 103 Suppl 1
- Issue:
- suppl 1
- Pages:
- S122
- Publication date:
- 2014-07-05
- DOI:
- EISSN:
-
1755-3245
- ISSN:
-
0008-6363
- URN:
-
uuid:8a188c37-9b01-435c-bf64-72f237b2d6a1
- Source identifiers:
-
475916
- Local pid:
- pubs:475916
Item Description
- Language:
- English
Terms of use
- Copyright date:
- 2014
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