Journal article
Application of copper(i) salt and fluoride promoted Stille coupling reactions in the synthesis of bioactive molecules
- Abstract:
- The Stille coupling between organostannanes and organohalides is an effective catalytic method for organic synthesis. Despite the ample amount of published results in this area, finding the optimal conditions for this transformation is often not straightforward. It was observed that this reaction could be accelerated with improved efficiency by the addition of a Cu(i) salt and fluoride. This review summarises the application of this simple protocol in the synthesis of natural products, their analogues and other biologically active molecules, from 2004 to 2018.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 724.1KB, Terms of use)
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- Publisher copy:
- 10.1039/c9ob01602c
Authors
- Publisher:
- Royal Society of Chemistry
- Journal:
- Organic and Biomolecular Chemistry More from this journal
- Volume:
- 17
- Pages:
- 9095-9123
- Publication date:
- 2019-09-20
- Acceptance date:
- 2019-09-18
- DOI:
- EISSN:
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1477-0539
- ISSN:
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1477-0520
- Pmid:
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31596305
- Language:
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English
- Keywords:
- Pubs id:
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pubs:1061697
- UUID:
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uuid:8a019372-9a60-4a91-9a5a-2bedbeb47ac0
- Local pid:
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pubs:1061697
- Source identifiers:
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1061697
- Deposit date:
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2019-11-05
Terms of use
- Copyright holder:
- Royal Society of Chemistry
- Copyright date:
- 2019
- Rights statement:
- © Royal Society of Chemistry 2019
- Notes:
-
This is the accepted manuscript version of the article. The final version is available from Royal Society of Chemistry at https://doi.org/10.1039/C9OB01602C
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