The hereditary predisposition to hip osteoarthritis and its association with abnormal joint morphology.

Journal article

OBJECTIVE: Genetic factors and abnormalities of joint morphology are important in the aetiology of hip osteoarthritis (OA). The extent to which genetic influences are manifest through joint morphology has undergone limited investigation. Using a cohort with an hereditary predisposition to end-stage hip OA and a control group with no inherited risk, we aimed to identify associations with abnormal joint morphology and clinical features. DESIGN: One hundred and twenty-three individuals (mean ag...

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Authors: Pollard, T; Batra, R; Judge, A; Watkins, B; McNally, E

• Publication status: Published
• Journal: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
• Volume: 21
• Issue: 2
• Pages: 314-321
• Publication date: 2013-02-01
• DOI: 10.1016/j.joca.2012.10.015
• EISSN: 1522-9653
• ISSN: 1063-4584
• Language: English
• Keywords: Femur; Case-Control Studies; Male; Adult; Longitudinal Studies; Acetabulum; Genetic Predisposition to Disease; Incidence; Cohort Studies; Confidence Intervals; Prospective Studies; Female; Humans; Osteoarthritis, Hip; Middle Aged; Hip Joint; Odds Ratio