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Thesis

Extensions of the case-control design in genome-wide association studies

Abstract:

The case-control design is one of the most commonly used designs in genome- wide asociation studies. When we increase the sample size of either the controls or, more importantly, the cases, the power of whatever test we use will certainly increase. However increasing the sample size, means that addi- tional individuals need to be genotyped and this implies extra financial costs. However, nowadays with the emergence of genetic studies, a large number of genetic data are available at low or ...

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Institution:
University of Oxford
Oxford college:
St Hugh's College
Department:
Mathematical,Physical & Life Sciences Division - Statistics

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Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:89e057e5-d30f-4125-b210-14d1f2aa37c1
Local pid:
ora:6493

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