- Abstract:
-
BACKGROUND: The vitamin D receptor (VDR) gene represents a strong positional candidate susceptibility gene for inflammatory bowel disease (IBD). The VDR gene maps to a region on chromosome 12 that has been shown to be linked to IBD by genome screening techniques. It is the cellular receptor for 1,25(OH)(2) vitamin D(3) (calcitriol) which has a wide range of different regulatory effects on the immune system. IBD is characterised by activation of the mucosal immune system. AIM: To determine if ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1136/gut.47.2.211
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- Journal:
- Gut
- Volume:
- 47
- Issue:
- 2
- Pages:
- 211-214
- Publication date:
- 2000-08-05
- DOI:
- EISSN:
-
1468-3288
- ISSN:
-
0017-5749
- URN:
-
uuid:89d93c27-eeeb-441f-b524-6805ef5cf2a3
- Source identifiers:
-
135296
- Local pid:
- pubs:135296
- Copyright date:
- 2000
Journal article
Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.
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