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Stimulation of naive T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms.

Abstract:

Chemokines adsorbed to the cell surface play an important role in the initial interactions of T cells with endothelial cells, and may also have a role in T-cell interactions with dendritic cells. Therefore, we examined the effect of surface-adsorbed chemokines on the interaction of naïve murine splenic T cells with supported bilayers containing intercellular adhesion molecule (ICAM)-1, or with bone marrow-derived cultured dendritic cells in the presence and absence of relevant MHC-peptide com...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Immunology More from this journal
Volume:
106
Issue:
3
Pages:
289-298
Publication date:
2002-07-01
DOI:
EISSN:
1365-2567
ISSN:
0019-2805
Language:
English
Keywords:
Pubs id:
pubs:482653
UUID:
uuid:89d8de49-ff31-43fa-9c97-7cca85c1e2b9
Local pid:
pubs:482653
Source identifiers:
482653
Deposit date:
2014-09-14

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