Journal article
Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency
- Abstract:
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BACKGROUND: Transcription factors play a key role in lineage commitment and differentiation of stem cells into distinct mature cells. In hematopoiesis, they regulate lineage-specific gene expression in a stage-specific manner through various physical and functional interactions with regulatory proteins that are simultanously recruited and activated to ensure timely gene expression. The transcription factor CCAAT/enhancer binding protein α (C/EBPα) is such a factor and is essential for the dev...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Publication date:
- 2012-01-01
- Acceptance date:
- 2012-05-11
- DOI:
- EISSN:
-
1932-6203
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:340077
- UUID:
-
uuid:89c9ac5b-0791-4906-8e6a-67ab70b441c9
- Local pid:
- pubs:340077
- Source identifiers:
-
340077
- Deposit date:
- 2013-11-16
Terms of use
- Copyright holder:
- Hasemann et al
- Copyright date:
- 2012
- Notes:
- © 2012 Hasemann et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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