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Relative contributions of inferior petrosal sinus sampling and pituitary imaging in the investigation of children and adolescents with ACTH-dependent Cushing's syndrome.

Abstract:

Selective transsphenoidal microadenomectomy is the first line treatment of childhood Cushing's disease, with accurate preoperative localization of the corticotroph adenoma an important step in its investigation. Inferior petrosal sinus sampling (IPSS) for ACTH after CRH stimulation is a recognized investigation in adults, but there are few data in the pediatric age range. We report the relative contributions of IPSS and pituitary imaging in 11 patients, aged 10.7-18.8 yr, presenting with Cush...

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Publication status:
Published

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Publisher copy:
10.1210/jc.86.12.5711

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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
86
Issue:
12
Pages:
5711-5714
Publication date:
2001-12-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:89b0c5b7-7aff-4a49-99e5-c8b20118f3e2
Source identifiers:
138348
Local pid:
pubs:138348

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