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Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial

Abstract:
Background Children with persistent hearing loss due to otitis media with effusion are commonly managed by surgical intervention. A safe, cheap, and effective medical treatment would enhance treatment options. Underpowered, poor-quality trials have found short-term benefit from oral steroids. We aimed to investigate whether a short course of oral steroids would achieve acceptable hearing in children with persistent otitis media with effusion and hearing loss. Methods... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1016/s0140-6736(18)31490-9

Authors


Francis, NA More by this author
Cannings-John, R More by this author
Waldron, C-A More by this author
Thomas-Jones, E More by this author
Winfield, T More by this author
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National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Journal website
Volume:
392
Issue:
10147
Pages:
557-568
Publication date:
2018-08-16
Acceptance date:
2018-06-27
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pubs id:
pubs:911245
URN:
uri:89917e09-d939-420a-9b5f-10ddad7eddeb
UUID:
uuid:89917e09-d939-420a-9b5f-10ddad7eddeb
Local pid:
pubs:911245
Language:
English
Keywords:

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