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Plagiarizing plants: amino sugars as a class of glycosidase inhibitors.

Abstract:

Many polyhydroxylated alkaloids from plants are specific inhibitors of glycosidases. Information about these has led to the development of a wide range of both naturally occurring and synthetic inhibitors which may be used for mechanistic studies and for the purification of these enzymes. Sugar lactones are starting materials for highly efficient syntheses of deoxymannojirimycin and deoxyfuconojirimycin and of a number of their iminoheptitol analogues. This has allowed an investigation of the...

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Authors


Fellows, LE More by this author
Winchester, B More by this author
Journal:
Ciba Foundation symposium
Volume:
154
Pages:
112-122
Publication date:
1990
ISSN:
0300-5208
URN:
uuid:89916a80-5aa1-41cd-87dd-2b5fa60322c0
Source identifiers:
52136
Local pid:
pubs:52136

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