- Abstract:
-
Impairment of CD4(+) T lymphocyte responses to human immunodeficiency virus (HIV)-derived antigens is the classic immunological defect observed during the chronic phase of HIV-1 infection. Early intervention with potent antiretroviral therapy (ART) can preserve HIV-specific CD4(+) T lymphocyte reactivity, providing indirect evidence that such responses are mounted during primary infection and subsequently lost in the majority of infected individuals. Here, we demonstrate early and dramatic ex...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/1521-4141(200112)31:12<3782::aid-immu3782>3.0.co;2-#
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- Journal:
- European journal of immunology
- Volume:
- 31
- Issue:
- 12
- Pages:
- 3782-3788
- Publication date:
- 2001-12-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:89869854-6d1b-45ee-a17a-02c18a01067a
- Source identifiers:
-
16995
- Local pid:
- pubs:16995
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
Variable fate of virus-specific CD4(+) T cells during primary HIV-1 infection.
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