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Optimal echo time for functional MRI of the infant brain identified in response to noxious stimulation

Abstract:
Purpose: Blood oxygen level dependent (BOLD) brain activity, measured using functional MRI (fMRI), is dependent on the echo time (TE) and the reversible spin–spin relaxation time constant (T! 2 ) that describes the decay of transverse magnetization. Use of the optimal TE during fMRI experiments allows maximal sensitivity to BOLD to be achieved. Reports that T! 2 values are longer in infants (due to higher water concentrations and lower lipid content) have led to the use of lo... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/mrm.26455

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Expand authors...
Wellcome Trust More from this funder
Publisher:
Wiley Publisher's website
Journal:
Magnetic Resonance in Medicine Journal website
Volume:
78
Issue:
2
Pages:
625–631
Publication date:
2016-09-21
Acceptance date:
2016-08-01
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Keywords:
Pubs id:
pubs:641076
UUID:
uuid:8982bfd4-2c21-4124-90f0-19f117620fe9
Local pid:
pubs:641076
Deposit date:
2016-08-31

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