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Pretreatment proliferation parameters do not add predictive power to clinical factors in cervical cancer treated with definitive radiation therapy.

Abstract:

PURPOSE: To examine the prognostic value of tumor proliferation measurements in women with carcinoma of the uterine cervix. We report an update of a prospective study focusing on whether pretreatment proliferation parameters are associated with clinical outcome, relative to other established clinical factors. MATERIALS AND METHODS: One hundred and one patients were recruited into the study from years 1991 to 1999. The LI for in vivo bromodeoxyuridine incorporation by the tumor and the potent...

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Pintilie, M More by this author
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Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
9
Issue:
12
Pages:
4387-4395
Publication date:
2003-10-05
ISSN:
1078-0432
URN:
uuid:897f0634-2bda-4196-8ff2-6602669ffbb0
Source identifiers:
400599
Local pid:
pubs:400599

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