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Genetic variability and linkage disequilibrium within the HLA-DP region: analysis of 15 different populations.

Abstract:

In order to understand the forces governing the evolution of the genetic diversity in the HLA-DP molecule, polymerase chain reaction (PCR)-based methods were used to characterize genetic variation at the DPA1 and DPB1 loci encoding this heterodimer on 2,807 chromosomes from 15 different populations including individuals of African, Asian, Amerindian, Indian and European origin. These ethnically diverse samples represent a variety of population substructures and include small, isolated populat...

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Publication status:
Published

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Journal:
Tissue antigens More from this journal
Volume:
57
Issue:
5
Pages:
424-439
Publication date:
2001-05-01
DOI:
EISSN:
1399-0039
ISSN:
0001-2815
Language:
English
Keywords:
Pubs id:
pubs:95382
UUID:
uuid:897e97f1-4960-4805-ab5a-3b1856db0694
Local pid:
pubs:95382
Source identifiers:
95382
Deposit date:
2012-12-19

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