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Spatiotemporal assessment of the cellular safety of cavitation-based therapies by passive acoustic mapping

Abstract:

Many useful therapeutic bio-effects can be generated using ultrasound-induced cavitation. However, cavitation is also capable of causing unwanted cellular and vascular damage, which should be monitored to ensure treatment safety. In this work, the unique opportunity provided by passive acoustic mapping (PAM) to quantify cavitation dose across an entire volume of interest during therapy is utilised to provide setup-independent measures of spatially localised cavitation dose. This spatiotempora...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ultrasmedbio.2020.01.009

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Publisher:
Elsevier
Journal:
Ultrasound in Medicine and Biology More from this journal
Volume:
46
Issue:
5
Pages:
1235-1243
Publication date:
2020-02-25
Acceptance date:
2020-01-13
DOI:
EISSN:
1879-291X
ISSN:
0301-5629
Pmid:
32111455
Language:
English
Keywords:
Pubs id:
1090473
Local pid:
pubs:1090473
Deposit date:
2020-03-02

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