Back to Search

Journal article

6R- and 6S-6C-Methylmannose from D-mannuronolactone. Inhibition of phosphoglucomutase and phosphomannomutase: agents for the study of the primary metabolism of mannose

Abstract:: The syntheses of 6S-3 and 6R-6 6C-methylmannoses rely on opposite and highly stereoselective reductions of fully and partially protected ketones derived from D-mannuronolactone, respectively. Reduction of the silylated ketone 2 by sodium borohydride was accompanied by complete migration of the silyl protecting group to the new stereogenic centre; the silyl migration was suppressed when the reduction was conducted in the presence of cerium(III) chloride. Both epimers were good inhibitors of ph...
Expand abstract
Collapse abstract

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Martin, A., Watterson, M., Brown, A., Imtiaz, F., Winchester, B. G., Watkin, D., & Fleet, G. (1999). 6R- and 6S-6C-Methylmannose from D-mannuronolactone. Inhibition of phosphoglucomutase and phosphomannomutase: agents for the study of the primary metabolism of mannose. TETRAHEDRON-ASYMMETRY, 10(2), 355–366.

MLA Style

Martin, A., et al. “6R- And 6S-6C-Methylmannose from D-Mannuronolactone. Inhibition of Phosphoglucomutase and Phosphomannomutase: Agents for the Study of the Primary Metabolism of Mannose.” TETRAHEDRON-ASYMMETRY, vol. 10, no. 2, 1999, pp. 355–66.

Chicago Style

Martin, A, M Watterson, A Brown, F Imtiaz, BG Winchester, D Watkin, and G Fleet. 1999. “6R- And 6S-6C-Methylmannose from D-Mannuronolactone. Inhibition of Phosphoglucomutase and Phosphomannomutase: Agents for the Study of the Primary Metabolism of Mannose.” TETRAHEDRON-ASYMMETRY 10 (2): 355–66.
Tweet
Print

Access Document

Publisher copy:: 10.1016/S0957-4166(98)00492-3

Authors

+ Martin, A More by this author

Role:

Author

+ Watterson, M More by this author

Role:

Author

+ Brown, A More by this author

Role:

Author

+ Imtiaz, F More by this author

Role:

Author

+ Winchester, BG More by this author

Role:

Author

More authors...

Bibliographic Details

Journal:: TETRAHEDRON-ASYMMETRY
Volume:: 10
Issue:: 2
Pages:: 355-366
Publication date:: 1999-01-29
DOI:: 10.1016/S0957-4166(98)00492-3
ISSN:: 0957-4166

Item Description

Language:: English
Pubs id:: pubs:36951
UUID:: uuid:89753fb9-0236-47ce-b2c6-89c06a312dd3
Local pid:: pubs:36951
Source identifiers:: 36951
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 1999

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Metrics

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP