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Journal article

Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens

Abstract:

Background: In humans and other animals, the chronic hypoxic response is mediated by hypoxia inducible transcription factors (HIFs) which regulate the expression of genes that counteract the effects of limiting oxygen. Prolyl hydroxylases (PHDs) act as hypoxia sensors for the HIF system in ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.2147/HP.S174655

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Organic Chemistry
Role:
Author
ORCID:
0000-0003-2141-5988
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Organic Chemistry
Role:
Author
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More from this funder
Funding agency for:
Abboud, MI
Leverhulme Trust More from this funder
National Institutes of Health More from this funder
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Publisher:
Dove Medical Press Publisher's website
Journal:
Hypoxia Journal website
Volume:
2018
Issue:
6
Pages:
57—71
Publication date:
2018-11-09
Acceptance date:
2018-07-27
DOI:
ISSN:
2324-1128
Pubs id:
pubs:915989
URN:
uri:897158b3-6c1e-4c70-aef4-a1deb6b38df1
UUID:
uuid:897158b3-6c1e-4c70-aef4-a1deb6b38df1
Local pid:
pubs:915989

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