- Abstract:
-
Background
Malaria parasites have evolved a series of intricate mechanisms to survive and propagate within host red blood cells. Intra-erythrocytic parasitism requires these organisms to digest haemoglobin and detoxify ironbound haem. These tasks are executed by haemoglobin-specific proteases and haem biocrystallization factors that are components of a large multi-subunit complex. Since haemoglobin processing machineries are functionally and genetically linked to the modes of acti...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 3.8MB)
-
- Publisher copy:
- 10.1186/s12936-016-1097-9
-
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- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria Journal Journal website
- Volume:
- 15
- Issue:
- 1
- Pages:
- 51
- Chapter number:
- ARTN 51
- Publication date:
- 2016-01-05
- DOI:
- EISSN:
-
1475-2875
- ISSN:
-
1475-2875
- URN:
-
uuid:896ed9ca-552b-4817-81f8-1f27d39deea4
- Source identifiers:
-
601492
- Local pid:
- pubs:601492
- Language:
- English
- Copyright holder:
- Ponsuwanna et al
- Copyright date:
- 2016
- Notes:
- © 2016 Ponsuwanna et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Journal article
Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites.
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Grand Challenges Canada
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Office of the Higher Education Commission
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Mahidol University
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