Journal article
Natriuretic peptides like NO facilitate cardiac vagal neurotransmission and bradycardia via a cGMP pathway.
- Abstract:
-
We tested the hypothesis that natriuretic peptide receptors (NPRs) that are coupled to cGMP production act in a similar way to nitric oxide (NO) by enhancing acetylcholine release and vagal-induced bradycardia. The effects of enzyme inhibitors and channel blockers on the action of atrial natriuretic peptide (ANP), brain-derived natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) were evaluated in isolated guinea pig atrial-right vagal nerve preparations. RT-PCR confirmed the prese...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- American journal of physiology. Heart and circulatory physiology
- Volume:
- 281
- Issue:
- 6
- Pages:
- H2318-H2327
- Publication date:
- 2001-12-05
- EISSN:
-
1522-1539
- ISSN:
-
0363-6135
- URN:
-
uuid:89696b3c-c9f0-48e1-baa1-c52d342d37e0
- Source identifiers:
-
105328
- Local pid:
- pubs:105328
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2001
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