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Effect of low-dose enflurane on the ventilatory response to hypoxia in humans.

Abstract:

To investigate the effects of enflurane on the control of breathing we have studied the ventilatory responses to isocapnic hypoxia in 12 adults with and without sedation with enflurane. Design 1 consisted of three steps into hypoxia (PE' O2 = 6.7 kPa), each lasting 3 min, separated by periods of euoxia lasting 5 min (PE' O2 = 13.3 kPa). Design 1 was repeated four times in each subject on the same day in random order: with carrier gas (control) and with 0.04 MAC, 0.07 MAC and 0.13 MAC of end-t...

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Publication status:
Published

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Publisher copy:
10.1093/bja/72.5.509

Authors


Nagyova, B More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
British journal of anaesthesia
Volume:
72
Issue:
5
Pages:
509-514
Publication date:
1994-05-05
DOI:
EISSN:
1471-6771
ISSN:
0007-0912
URN:
uuid:896481ba-b6ee-4ea6-90b1-82c002b6ae98
Source identifiers:
113501
Local pid:
pubs:113501

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