Transcriptional collision between convergent genes in budding yeast.

Journal article

Abstract:: Transcriptional interference between genes and the regulatory elements of simple eukaryotes such as Saccharomyces cerevisiae is an unavoidable consequence of their compressed genetic arrangement. We have shown previously that with the tandem arranged genes GAL10 and GAL7, inefficient transcriptional termination of the upstream gene inhibits initiation of transcription on the downstream gene. We now show that transcriptional interference can occur also with S. cerevisiae RNA polymerase II gene...
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Role:

Author

Institution:

University of Oxford

Division:

MSD

Department:

Pathology Dunn School

Role:

Author

Journal:: Proceedings of the National Academy of Sciences of the United States of America
Volume:: 99
Issue:: 13
Pages:: 8796-8801
Publication date:: 2002-06-01
DOI:: 10.1073/pnas.132270899
EISSN:: 1091-6490
ISSN:: 0027-8424

Language:: English
Keywords:: Transcription, Genetic

Base Sequence

Saccharomyces cerevisiae

Blotting, Northern

Genes, Fungal

DNA Primers
Pubs id:: pubs:28620
UUID:: uuid:89644204-d072-4588-9124-2adbf97b8aca
Local pid:: pubs:28620
Source identifiers:: 28620
Deposit date:: 2012-12-19

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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