Journal article icon

Journal article

Non-linear relationships of cerebrospinal fluid biomarker levels with cognitive function: an observational study.

Abstract:

INTRODUCTION: Levels of cerebrospinal fluid (CSF) β-amyloid (Aβ) and Tau proteins change in Alzheimer's disease (AD). We tested if the relationships of these biomarkers with cognitive impairment are linear or non-linear. METHODS: We assessed cognitive function and assayed CSF Aβ and Tau biomarkers in 95 non-demented volunteers and 97 AD patients. We then tested non-linearities in their inter-relations. RESULTS: CSF biomarkers related to cognitive function in the non-demented range of cogniti...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1186/alzrt64

Authors


More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Stroke and Geratology
Role:
Author
More from this funder
Name:
NIHR Oxford Biomedical Research Centre
Funding agency for:
Williams, J
Wilcock, G
More from this funder
Name:
Shigeo and Megumi Takayama Foundation
Funding agency for:
Williams, J
Publisher:
BioMed Central
Journal:
Alzheimer's Research and Therapy More from this journal
Volume:
3
Issue:
1
Article number:
5
Publication date:
2011-01-01
DOI:
EISSN:
1758-9193
ISSN:
1758-9193
Language:
English
Pubs id:
pubs:127145
UUID:
uuid:89509b70-2685-4ec4-afb2-9e3a38c9d6b8
Local pid:
pubs:127145
Source identifiers:
127145
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP