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Recall proliferation potential of memory CD8+ T cells and antiviral protection.

Abstract:

Memory CD8+ T cells play a crucial role in mediating protection from infection with viruses and other intracellular pathogens. Memory T cells are not a homogenous cellular population and may be separated into central memory T cells with substantial recall proliferation capacity and effector memory T cells with limited recall proliferation capacity. It has been suggested that the protective capacity of effector memory T cells is more limited than that of central memory T cells in viral infecti...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.175.7.4677

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Journal of Immunology
Volume:
175
Issue:
7
Pages:
4677-4685
Publication date:
2005-10-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Source identifiers:
469781

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