- Abstract:
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Single nucleotide polymorphisms (SNPs) have great potential to serve as important biomarkers in the clinic to identify those at increased risk for developing cancer, progressing more rapidly, and not responding to therapies. However, the clinical application of cancer-associated SNPs has proven to be more complicated than expected. One of the necessary steps will certainly be the description of the molecular and cellular mechanisms behind the observed associations. The p53 tumour suppresso...
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- Funding agency for:
- Jorge Zeron-Medina Cuairan
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- URN:
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uuid:8942602e-c0f8-4793-8020-d2eadd41b252
- Local pid:
- ora:8848
- Copyright holder:
- Jorge Zeron-Medina Cuairan
- Copyright date:
- 2013
Thesis
The identification and characterisation of germline genetic variants that affect human cancer
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+ Clarendon Fund (University of Oxford)
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