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Cell cycle regulation of tubulin RNA level, tubulin protein synthesis, and assembly of microtubules in Physarum.

Abstract:

The temporal relationship between tubulin expression and the assembly of the mitotic spindle microtubules has been investigated during the naturally synchronous cell cycle of the Physarum plasmodium. The cell cycle behavior of the tubulin isoforms was examined by two-dimensional gel electrophoresis of proteins labeled in vivo and by translation of RNA in vitro. alpha 1-, alpha 2-, beta 1-, and beta 2-tubulin synthesis increases coordinately until metaphase, and then falls, with beta 2 falling...

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Publication status:
Published

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Publisher copy:
10.1083/jcb.99.1.155

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of cell biology
Volume:
99
Issue:
1 Pt 1
Pages:
155-165
Publication date:
1984-07-01
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
Source identifiers:
8259
Language:
English
Keywords:
Pubs id:
pubs:8259
UUID:
uuid:8937aeef-d1cb-4328-aed7-ecd0ca0953f1
Local pid:
pubs:8259
Deposit date:
2012-12-19

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