Evidence and implications of mortality associated with acute Plasmodium vivax malaria.

Journal article

Vivax malaria threatens patients despite relatively low-grade parasitemias in peripheral blood. The tenet of death as a rare outcome, derived from antiquated and flawed clinical classifications, disregarded key clinical evidence, including (i) high rates of mortality in neurosyphilis patients treated with vivax malaria; (ii) significant mortality from zones of endemicity; and (iii) the physiological threat inherent in repeated, very severe paroxysms in any patient, healthy or otherwise. The v...

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Authors: Baird, J

• Publication status: Published
• Journal: Clinical microbiology reviews
• Volume: 26
• Issue: 1
• Pages: 36-57
• Publication date: 2013-01-01
• DOI: 10.1128/cmr.00074-12
• EISSN: 1098-6618
• ISSN: 0893-8512
• Language: English
• Keywords: Plasmodium vivax; Humans; Spleen; Blood; Bone Marrow; Malaria, Vivax; Parasitemia