Journal article icon

Journal article

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'.

Abstract:

BACKGROUND: Blood concentrations of fibrinogen have been associated with coronary heart disease risk in epidemiological studies, but it is uncertain whether this association is causal or reflects residual confounding by other risk factors. We investigated the relationship between the single nucleotide polymorphism at position -148 in the beta-fibrinogen gene promoter (beta - 148C/T), blood fibrinogen levels, and risk of myocardial infarction (MI) in sufficiently large numbers of coronary dis...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/ije/dyl114

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
Expand authors...
Journal:
International journal of epidemiology
Volume:
35
Issue:
4
Pages:
935-943
Publication date:
2006-08-01
DOI:
EISSN:
1464-3685
ISSN:
0300-5771
Source identifiers:
40058
Language:
English
Keywords:
Pubs id:
pubs:40058
UUID:
uuid:891dc44b-23d9-4a45-b41c-705d5009ec97
Local pid:
pubs:40058
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP