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K13-propeller mutations in Plasmodium falciparum populations in malaria endemic regions of Vietnam from 2009 to 2016

Abstract:

The spread of artemisinin resistant P. falciparum compromises the therapeutic efficacy of artemisinin combination therapies (ACT) and is considered the greatest threat to current global initiatives to control and eliminate malaria. This is particularly relevant for Vietnam, where dihydroartemisinin-piperaquine (DP) is the recommended ACT for P. falciparum The propeller domain gene of K13, a molecular marker of artemisinin resistance, was sequenced successfully in 1060 P. falciparum isolates c...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/AAC.01578-16

Authors


Publisher:
American Society for Microbiology Publisher's website
Journal:
Antimicrobial Agents and Chemotherapy Journal website
Volume:
61
Issue:
4
Pages:
e01578-16
Publication date:
2017-01-30
Acceptance date:
2017-01-22
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
Language:
English
Keywords:
Pubs id:
pubs:675288
UUID:
uuid:89050c66-4125-4d04-b0a8-cb7a1c6cbba9
Local pid:
pubs:675288
Source identifiers:
675288
Deposit date:
2017-02-15

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