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Differentiated baroreflex modulation of sympathetic nerve activity during deep brain stimulation in humans.

Abstract:

Targeted electric deep brain stimulation in midbrain nuclei in humans alters cardiovascular parameters, presumably by modulating autonomic and baroreflex function. Baroreflex modulation of sympathetic outflow is crucial for cardiovascular regulation and is hypothesized to occur at 2 distinct brain locations. The aim of this study was to evaluate sympathetic outflow in humans with deep brain stimulating electrodes during ON and OFF stimulation of specific midbrain nuclei known to regulate card...

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Publication status:
Published

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Authors


Sverrisdóttir, YB More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Bahuri, NF More by this author
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Journal:
Hypertension
Volume:
63
Issue:
5
Pages:
1000-1010
Publication date:
2014-05-05
DOI:
EISSN:
1524-4563
ISSN:
0194-911X
URN:
uuid:88f7bb3e-a9d2-4319-9ab7-008f794b9c39
Source identifiers:
449221
Local pid:
pubs:449221

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