- Abstract:
-
The ATP-sensitive potassium (KATP) channel is a hetero-octameric complex that links cell metabolism to membrane electrical activity in many cells, thereby controlling physiological functions such as insulin release, muscle contraction and neuronal activity. It consists of four pore-forming Kir6.2 and four regulatory sulfonylurea receptor (SUR) subunits. SUR2B serves as the regulatory subunit in smooth muscle and some neurones. An integrative approach, combining electron microscopy and homolog...
Expand abstract - Publisher copy:
- 10.1111/febs.12097
-
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- Journal:
- FEBS Journal
- Volume:
- 280
- Issue:
- 4
- Pages:
- 1051-1063
- Publication date:
- 2013-02-05
- DOI:
- EISSN:
-
1742-4658
- ISSN:
-
1742-464X
- URN:
-
uuid:88ef9602-1e1b-4ce2-a940-6836ac0334f4
- Source identifiers:
-
388210
- Local pid:
- pubs:388210
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles
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