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Do height-related variations in insulin-like growth factors underlie the associations of stature with adult chronic disease?

Abstract:

Tall people, particularly those with long legs, have an increased risk of developing cancer but a reduced risk of cardiovascular disease and type II diabetes. We examined associations of stature and body mass index with IGF-I, IGF-II, and IGF binding protein (IGFBP)-2 and IGFBP-3 in 274 men aged 50-70 yr to investigate whether variations in growth factor levels underlie associations of anthropometry with a number of adult diseases. Height and leg and trunk length were not strongly associated ...

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Publication status:
Published

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Publisher copy:
10.1210/jc.2003-030507

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Journal:
Journal of clinical endocrinology and metabolism
Volume:
89
Issue:
1
Pages:
213-218
Publication date:
2004-01-01
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Source identifiers:
120596

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