Journal article icon

Journal article

Modeling and analysis of a virus that replicates selectively in tumor cells.

Abstract:

Replication-competent viruses have shown considerable promise in overcoming the inefficient gene transduction experienced by traditional gene therapy approaches to cancer treatment. The viruses infect tumor cells and replicate inside them, eventually causing lysis. Virus particles released during lysis are then able to infect other tumor cells, and, in this way, continuous rounds of infection and lysis allow the virus to spread throughout the tumor. Motivated by this novel cancer treatment, w...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1006/bulm.2001.0245

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
Bulletin of mathematical biology
Volume:
63
Issue:
4
Pages:
731-768
Publication date:
2001-07-05
DOI:
EISSN:
1522-9602
ISSN:
0092-8240
URN:
uuid:88aaa67f-e20d-4cf9-afa3-1863d298b50a
Source identifiers:
319133
Local pid:
pubs:319133

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP