Journal article
Deep and frequent phenotyping study protocol: an observational study in Prodromal Alzheimer’s Disease
- Abstract:
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Introduction Recent failures of potential novel therapeutics for Alzheimer’s disease (AD) have prompted a drive towards clinical studies in prodromal or preclinical states. However carrying out clinical trials in early disease stages is extremely challenging – a key reason being the unfeasibility of using classical outcome measures of dementia trials (for example conversion to dementia) and the lack of validated surrogate measures so early in the disease process. The Deep an... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 541.7KB, Terms of use)
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- Publisher copy:
- 10.1136/bmjopen-2018-024498
Authors
Bibliographic Details
- Publisher:
- BMJ Publishing Group
- Journal:
- BMJ Open More from this journal
- Volume:
- 9
- Issue:
- 3
- Publication date:
- 2019-03-23
- Acceptance date:
- 2019-01-23
- DOI:
- EISSN:
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2044-6055
Item Description
- Keywords:
- Pubs id:
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pubs:965758
- UUID:
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uuid:88a46146-ca5a-45b3-a8ee-b16753c27a96
- Local pid:
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pubs:965758
- Source identifiers:
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965758
- Deposit date:
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2019-01-24
Terms of use
- Copyright holder:
- Koychev et al
- Copyright date:
- 2019
- Notes:
- © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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