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Antigenic variation at the infected red cell surface in malaria.

Abstract:

Many pathogens that either rely on an insect vector to complete their life cycle (e.g., Trypanosoma spp. and Borrelia spp.) or exist in a unique ecological niche where transmission from host to host is sporadic (e.g., Neisseria spp.) have evolved strategies to maintain infection of their mammalian hosts for long periods of time in order to ensure their survival. Because they have to survive in the face of a fully functional immune system, a common feature of many of these organisms is their d...

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Publication status:
Published

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Authors


Horrocks, P More by this author
Newbold, C More by this author
Journal:
Annual review of microbiology
Volume:
55
Issue:
1
Pages:
673-707
Publication date:
2001
DOI:
EISSN:
1545-3251
ISSN:
0066-4227
URN:
uuid:88642af6-0888-4756-8c57-1d8278bbe7ee
Source identifiers:
94858
Local pid:
pubs:94858

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